Vancomycin heteroresistance in Staphylococcus haemolyticus: elusive phenotype

Vancomycin heteroresistance and methicillin-resistant Staphylococcus aureus.

Heteroresistance refers to the presence, within a larger population of fully antimicrobial-susceptible microorganisms, of subpopulations with lesser susceptibility. This phenomenon has been described in a wide range of microorganisms, but much recent attention has been directed toward its expression in Staphylococcus aureus. Although it has long been known that resistance to methicillin is char...

Vancomycin Heteroresistance in Methicillin-resistant Staphylococcus aureus, Taiwan

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Vancomycin heteroresistance in bloodstream isolates of Staphylococcus capitis.

Nine Staphylococcus capitis isolates from blood cultures of newborns were examined for resistance to vancomycin. MICs were within the susceptible range, but population profiling revealed a resistant subpopulation. Only isolates with the largest subpopulation were identified as heteroresistant to vancomycin by Etest. This finding may have therapeutic implications.

Vancomycin heteroresistance of Staphylococcus capitis 1 bloodstream isolates

Staphylococcus epidermidis with intermediate resistance to vancomycin: elusive phenotype or laboratory artifact?

The recent and troubling isolation of Staphylococcus aureus and coagulase-negative staphylococci that have increased resistance to glycopeptide antibiotics has prompted the use of aggressive surveillance measures in the clinical microbiology laboratory to aid in the recognition of these strains. Despite increasing awareness, the confirmation of glycopeptide resistance among staphylococci can be...